Research chemical sequence

Pancragen

Pancragen is listed as a research-use-only chemical sequence. Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.

Research-use boundary: Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.

Public identity

Publication state
unpublished
Sequence
Lys-Glu-Asp-Pro
IUPAC name
N-L-lysyl-L-alpha-glutamyl-L-alpha-aspartyl-L-proline
Molecular formula
C20H33N5O9

Available variants

Published product variants and USD prices
SizeSKUPrice (USD)AvailabilityRepresentative purity
20mgDFP-009$0.00Out of stock99.5%

Analytical boundary

Representative catalog purity: 99.5%

No active-batch certificate of analysis is currently published.

Purity figures shown here are representative catalog specifications, not lot-specific measurements.

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Evidence inventory

Record state
citation records
Public records
22
Reviewed summaries
0
Verified citations
0
  • Human study: 4
  • In vivo: 8
  • In vitro: 10
  • Special category: 0
  • Unclassified: 0

These counts describe linked records and review status. They do not establish efficacy, safety, or fitness for any use.

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Technical record

CAS number
110431-82-4
Molecular weight
502.5 Da
Sequence class
peptide
Molecular formula
C20H33N5O9
Appearance
White to off-white lyophilized powder
Solubility
Hydrophilic. Readily soluble in water (e.g., ultrapure water, PBS pH 7.4) at concentrations up to 10 mg/mL. For optimal stability, reconstitute immediately prior to use and store aliquots at -20°C or below.
Mechanism record
Pancragen (Lys-Glu-Asp-Trp) is a Khavinson 4-residue chemical sequence bioregulator targeting pancreatic islet cells. It binds AT-rich DNA motifs in pancreatic gene promoter regions, stimulating beta-cell insulin synthesis and modulating glucose-dependent gene expression. Studies show improved glucose tolerance and normalized insulin secretion patterns in aging animal models.
Half-life record
~20–30 minutes (SubQ, plasma)

Recorded receptors

  • Pancreatic beta-cell receptors
  • islet cell gene expression targets

External literature records

  1. External literature record

Limitations and research boundary

Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.

External records are attributed references. Their presence does not convert a source-reported observation into a product claim.