Study type: In vivo/preclinical · Status: Verified against declared source

Targeting mitochondria in the aged cerebral vasculature with SS-31, a proteomic study of brain microvessels.

GeroScience · 2023

Study scale: Aging has profound effects on vascular structure and function.

Abstract only: Open source record

Product or molecular entity relationships

SS-31: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Not reported in the reviewed source.

Methods

There were a few limitations to our study.

Scale or participants

Aging has profound effects on vascular structure and function.

Key findings

Cognitive impairment and dementias during aging such as Alzheimer’s disease are linked to functional decline and structural alterations of the brain microvasculature.

Limitations and uncertainty

Cognitive impairment and dementias during aging such as Alzheimer’s disease are linked to functional decline and structural alterations of the brain microvasculature.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.