Research chemical sequence
ARA-290
ARA-290 is listed as a research-use-only chemical sequence. Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
Research-use boundary: Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
Public identity
- Publication state
- unpublished
- Sequence
- pyroGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
Available variants
| Size | SKU | Price (USD) | Availability | Representative purity |
|---|---|---|---|---|
| 5mg | DFP-024 | $0.00 | Out of stock | 99.4% |
Analytical boundary
Representative catalog purity: 99.4%
No active-batch certificate of analysis is currently published.
Purity figures shown here are representative catalog specifications, not lot-specific measurements.
Evidence inventory
- Record state
- reviewed records
- Public records
- 144
- Reviewed summaries
- 16
- Verified citations
- 0
- Human study: 30
- In vivo: 96
- In vitro: 18
- Special category: 0
- Unclassified: 0
These counts describe linked records and review status. They do not establish efficacy, safety, or fitness for any use.
Technical record
- Molecular weight
- 1382.5 Da
- Sequence class
- peptide
- Appearance
- Lyophilized Solid
- Solubility
- Water, PBS, or 0.9% NaCl
- Mechanism record
- ARA-290 is an 11-amino-acid synthetic chemical sequence that selectively activates the innate repair receptor (IRR), a heterodimer of EPOR/βcR (erythropoietin receptor / beta common receptor). Unlike erythropoietin, ARA-290 does not stimulate erythropoiesis. It activates anti-apoptotic JAK2/STAT5 and PI3K/Akt signaling, providing cytoprotection in ischemic, inflammatory, and neuropathic tissue models.
- Half-life record
- ~2 minutes (plasma); sustained tissue-protective effect >12h
Recorded receptors
- IRR (EPOR-βcR heterodimer)
- anti-apoptotic
- NF-κB
External literature records
- External literature record
- External literature record
Limitations and research boundary
Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
External records are attributed references. Their presence does not convert a source-reported observation into a product claim.