Study type: In vivo/preclinical · Status: Verified against declared source
Cerebrolysin Attenuates Exacerbation of Neuropathic Pain, Blood-spinal Cord Barrier Breakdown and Cord Pathology Following Chronic Intoxication of Engineered Ag, Cu or Al (50-60 nm) Nanoparticles.
Neurochemical research · 2023
Study scale: Values are Mean ± SD of 6–8 rats at each point.
Abstract only: Open source record
Product or molecular entity relationships
- Cerebrolysin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Plain-language verified summary
Question
Not reported in the reviewed source.
Methods
Keeping these views in consideration, we examined the effect of engineered metal nanoparticles Ag, Cu and Al (50–60 nm) on chronic constriction nerve injury induced neuropathic pain in the rat on behavioural, biochemical and pathophysiological aspects in our laboratory.
Scale or participants
Values are Mean ± SD of 6–8 rats at each point.
Key findings
Neuropathic pain is associated with abnormal sensations and/or pain induced by non-painful stimuli, i.e., allodynia causing burning or cold sensation, pinching of pins and needles like feeling, numbness, aching or itching.
Limitations and uncertainty
Neuropathic pain is associated with abnormal sensations and/or pain induced by non-painful stimuli, i.e., allodynia causing burning or cold sensation, pinching of pins and needles like feeling, numbness, aching or itching.
Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.