Ipamorelin

Public identity

Publication state

unpublished

Sequence

Aib-His-D-2-Nal-D-Phe-Lys-NH2

Available variants

Analytical boundary

Representative catalog purity: 99.7%

No active-batch certificate of analysis is currently published.

Purity figures shown here are representative catalog specifications, not lot-specific measurements.

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Evidence inventory

Record state

citation records

Public records

78

Reviewed summaries

0

Verified citations

0

• Human study: 18
• In vivo: 42
• In vitro: 18
• Special category: 0
• Unclassified: 0

These counts describe linked records and review status. They do not establish efficacy, safety, or fitness for any use.

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Technical record

Molecular weight

711.9 Da

Sequence class

peptide

Appearance

Lyophilized Solid

Solubility

Water, PBS, or 0.9% NaCl

Mechanism record

Ipamorelin is a selective 5-residue chemical sequence growth hormone secretagogue that binds GHS-R1a (ghrelin receptor) on anterior pituitary somatotrophs. It activates intracellular Ca²⁺ mobilization and PKC signaling to trigger GH vesicle exocytosis. Highly selective, does not significantly increase cortisol, ACTH, prolactin, or aldosterone at physiological doses, distinguishing it from GHRP-6 and hexarelin.

Half-life record

~2 hours

Recorded receptors

• GHS-R1a
• Ca²⁺ mobilization
• PKC activation

External literature records

1. External literature record
2. External literature record

Limitations and research boundary

Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.

External records are attributed references. Their presence does not convert a source-reported observation into a product claim.