Study type: Human research · Status: Verified against declared source

Evaluation of Coronary Flow Level with Mots-C in Patients with STEMI Undergoing Primary PCI.

Arquivos brasileiros de cardiologia · 2023

Study scale: The study methodology was designed according to the article by Baylan et al.

Abstract only: Open source record

Product or molecular entity relationships

  • MOTS-c: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

We aimed to investigate the role of MOTS-C, which is known to have cytoprotective properties in the pathogenesis of the no-reflow phenomenon, by comparing the coronary flow rate and MOTS-C levels in patients with STEMI submitted to primary PCI.

Methods

The study methodology was designed according to the article by Baylan et al.

Scale or participants

The study methodology was designed according to the article by Baylan et al.

Key findings

52 pacientes com IAMCSST e 42 pacientes sem estenose >50% nas artérias coronárias foram incluídos no estudo.

Limitations and uncertainty

The protective effects of mitochondrial open reading frame of the 12S rRNA-c (MOTS-C) on cardiovascular diseases have been shown in numerous studies.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.