Study type: In vivo/preclinical · Status: Verified against declared source

Humanin: a novel central regulator of peripheral insulin action.

PloS one · 2009

Study scale: Not reported

Abstract only: Open source record

Product or molecular entity relationships

Humanin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Not reported in the reviewed source.

Methods

Under basal insulin levels during pancreatic-euglycemic clamp (1.42±0.08 vs.

Scale or participants

Not reported in the reviewed source.

Key findings

Using state of the art clamp technology, we examined the role of central and peripheral HN on insulin action.

Limitations and uncertainty

We conclude that the decline in HN with age could play a role in the pathogenesis of age-related diseases including AD and T2DM.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.