Study type: In vitro · Status: Verified against declared source

Thymosin Alpha 1 Mitigates Cytokine Storm in Blood Cells From Coronavirus Disease 2019 Patients.

Open forum infectious diseases · 2021

Study scale: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a potentially fatal disease of great global concern for public health.

Abstract only: Open source record

Product or molecular entity relationships

  • Thymosin Alpha 1: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a potentially fatal disease of great global concern for public health.

Methods

Correlations between immunophenotyping and cytokines transcriptional activity in coronavirus disease 2019 (COVID-19) individuals and modulation by Thymosin alpha 1 (Tα1) in vitro treatment.

Scale or participants

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a potentially fatal disease of great global concern for public health.

Key findings

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a potentially fatal disease of great global concern for public health.

Limitations and uncertainty

In the last few months, several studies characterized COVID-19 as a disease distinguishable by hyperinflammation and immune-mediated lung injury.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.