Study type: In vivo/preclinical · Status: Verified against declared source

Comparative neuroprotective effects of Cerebrolysin, dexamethasone, and ascorbic acid on sciatic nerve injury model: Behavioral and histopathological study

2023

Study scale: Rat care and all experimental procedures including surgery, behavior tests, and tissue collection were carried out following the Research Ethics Committee, Faculty of Veterinary Medicine, Mansoura University code No: R/138.

Abstract only: Open source record

Product or molecular entity relationships

  • Cerebrolysin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Five randomly selected sections of each animal in each group were studied under a 40X objective (area: 0.071 mm2).

Methods

Vitamin C is a promising therapeutic in the treatment of PNI.

Scale or participants

Rat care and all experimental procedures including surgery, behavior tests, and tissue collection were carried out following the Research Ethics Committee, Faculty of Veterinary Medicine, Mansoura University code No: R/138.

Key findings

The majority of the suggested experimental modalities for peripheral nerve injury (PNI) result in varying degrees of recovery in animal models; however, there are not many reliable clinical pharmacological treatment models available.

Limitations and uncertainty

The majority of the suggested experimental modalities for peripheral nerve injury (PNI) result in varying degrees of recovery in animal models; however, there are not many reliable clinical pharmacological treatment models available.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.