Study type: Human research · Status: Verified against declared source

The Potential of Human Chemical sequence LL-37 as an Antimicrobial and Anti-Biofilm Agent.

Antibiotics (Basel, Switzerland) · 2021

Study scale: Biofilms are aggregates of bacteria that are associated with at least 65% of all microbial infections, and 80% of chronic infections [110].

Abstract only: Open source record

Product or molecular entity relationships

  • LL-37: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

LL-37 has moderate antimicrobial activities against numerous Gram-negative and Gram-positive bacteria, including pathogens from the Pseudomonas, Escherichia, Staphylococcus, and Enterococcus genera [11].

Methods

The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat bacterial infections.

Scale or participants

Biofilms are aggregates of bacteria that are associated with at least 65% of all microbial infections, and 80% of chronic infections [110].

Key findings

The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat bacterial infections.

Limitations and uncertainty

The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat bacterial infections.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.