Study type: In vivo/preclinical · Status: Verified against declared source

Effect of Kvass on Improving Functional Dyspepsia in Rats.

Computational and mathematical methods in medicine · 2022

Study scale: Gastrointestinal disorders include gastrointestinal motility disorders (GIMD) and functional gastrointestinal diseases (FGID) [6, 7], mainly involving gastroesophageal reflux disease (GERD), functional dyspepsia (FD), irritable bowel syndrome (IBS), and chronic constipation.

Abstract only: Open source record

Product or molecular entity relationships

  • VIP: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

The purpose of this study is to explore the ability of kvass to alleviate the symptoms of FD and to explore the pharmacological effects of Kvass on gastrointestinal hormones and brain gut peptides in FD rats, particularly, the indexes related to FD, including body weight, food intake, plasma ghrelin, MTL, GAS, VIP, and other routine indexes.

Methods

Male Wistar rats were purchased (male, SPF grade, weight 180 ± 20 g, Changchun Yisi Experimental Animal Technology Co., Ltd., license No.

Scale or participants

Gastrointestinal disorders include gastrointestinal motility disorders (GIMD) and functional gastrointestinal diseases (FGID) [6, 7], mainly involving gastroesophageal reflux disease (GERD), functional dyspepsia (FD), irritable bowel syndrome (IBS), and chronic constipation.

Key findings

Functional dyspepsia (FD) is a common digestive system disease, and probiotics in the treatment of FD have a good curative effect.

Limitations and uncertainty

At present, the main drugs used in the treatment of FD are proton pump inhibitors (PPI), other acid inhibitors [23], prokinetic agents, and neuromodulators for visceral hypersensitivity, probiotics, and herbal therapy [24].

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.