Study type: In vivo/preclinical · Status: Verified against declared source

The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis.

Bioengineered · 2022

Study scale: Not reported

Abstract only: Open source record

Product or molecular entity relationships

  • Humanin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Humanin (HNG) is a peptide first discovered by Professor Hashimoto in Keio University during their investigations on brain tissues isolated from Alzheimer’s Disease patients.

Methods

Primary BMDMs were isolated from the bone marrow of C57BL/6 mice (n = 10).

Scale or participants

Not reported in the reviewed source.

Key findings

Gout is a common and complex form of arthritis that has brought great inconveniences to the normal lives of patients.

Limitations and uncertainty

Gout is a common and complex form of arthritis that has brought great inconveniences to the normal lives of patients.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.