Study type: In vivo/preclinical · Status: Verified against declared source

Cerebrolysin Prevents Brain Injury in a Mouse Model of Liver Damage

2021

Study scale: Liver damage is an important cause of mortality and morbidity worldwide.

Abstract only: Open source record

Product or molecular entity relationships

Cerebrolysin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Not reported in the reviewed source.

Methods

Nine-week-old C57BL/6 J male (n = 13) and female (n = 12) mice housed in rooms with controlled temperature (21–23 °C) and humidity (60–70%), on a 12 h/12 h light/dark cycle, with ad libitum access to food and tap water, were used for this study.

Scale or participants

Liver damage is an important cause of mortality and morbidity worldwide.

Key findings

Given all evidence of cortical changes in patients with liver damage [5,23] and the long-term implication of such changes, a neuroprotective treatment may be considered.

Limitations and uncertainty

Liver damage is an important cause of mortality and morbidity worldwide.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.