Study type: In vivo/preclinical · Status: Evidence verified by machine against declared source
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Molecular pain · 2024
Study scale: Male C57BL/6 mice (weighing 20–22 g, 8–10 weeks-old) were purchased from the Experimental Animal Center of Xuzhou Medical University (Xuzhou, China).
Abstract only: Open source record
Product or molecular entity relationships
- MOTS-c: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Public plain-language summary
Some fields are not published, because the text held for them did not answer their heading. The published text is limited to the declared source and preserves reported uncertainty. It does not establish efficacy, safety, suitability, or evidence strength.
Research question
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Study design
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Participants or experimental system
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Study scale
Male C57BL/6 mice (weighing 20–22 g, 8–10 weeks-old) were purchased from the Experimental Animal Center of Xuzhou Medical University (Xuzhou, China).
Intervention or exposure
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Comparator
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Outcomes examined
The mechanical pain threshold of mice was measured by von Frey monofilaments (Bio-VF-M, Bioseb, USA) with the up-down method.
Key findings
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Limitations and uncertainty
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Product relevance and evidence boundary
This record is a published study, held here with its citation and review status. It is not a statement that any catalog item is effective, safe, or suitable for any use, and nothing in it is a dose or a protocol.
Evidence verified by machine against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.