Study type: In vivo/preclinical · Status: Verified against declared source
Behavioral-state modulation of inhibition is context-dependent and cell type specific in mouse visual cortex.
eLife · 2016
Study scale: (A) Left panels, scatter plots of the locomotion modulation index (LMI) of individual neurons in darkness versus during visual stimulation (gratings) with an associated Pearson correlation coefficient (R-values).
Abstract only: Open source record
Product or molecular entity relationships
- VIP: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Plain-language verified summary
Question
Imaging was performed using a custom-built resonant scanning two-photon microscope with a Ti:Sapphire pulsing laser (Chameleon Vision-S, Coherent, CA, USA; < 70 fs pulse width, 80 MHz repetition rate) tuned to 920 nm.
Methods
(A) Left panels, scatter plots of the locomotion modulation index (LMI) of individual neurons in darkness versus during visual stimulation (gratings) with an associated Pearson correlation coefficient (R-values).
Scale or participants
(A) Left panels, scatter plots of the locomotion modulation index (LMI) of individual neurons in darkness versus during visual stimulation (gratings) with an associated Pearson correlation coefficient (R-values).
Key findings
Cortical responses to sensory stimuli are modulated by behavioral state.
Limitations and uncertainty
How we perceive what we see depends on the context in which we see it, such as what we are doing at the time.
Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.