Study type: Human research · Status: Verified against declared source
Both objective and paradoxical insomnia elicit a stress response involving mitokine production.
Aging · 2020
Study scale: The onset and perpetuation of IN are considered associated with the activation of the Hypothalamic-pituitary-adrenal (HPA) axis with a consequent release of key molecules, such as cortisol hormone [7].
Abstract only: Open source record
Product or molecular entity relationships
- Humanin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Plain-language verified summary
Question
Chronic insomnia is the most common sleep disorder in the elderly population.
Methods
Not reported in the reviewed source.
Scale or participants
The onset and perpetuation of IN are considered associated with the activation of the Hypothalamic-pituitary-adrenal (HPA) axis with a consequent release of key molecules, such as cortisol hormone [7].
Key findings
Chronic insomnia is the most common sleep disorder in the elderly population.
Limitations and uncertainty
Chronic insomnia is the most common sleep disorder in the elderly population.
Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.