Study type: Human research · Status: Verified against declared source
Life-Threatening Anaphylaxis due to Cerebrolysin®
2024
Study scale: Not reported
Abstract only: Open source record
Product or molecular entity relationships
- Cerebrolysin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Plain-language verified summary
Question
In this case report, we describe a well-documented, severe anaphylactic reaction after intravenous administration of cerebrolysin, a neurotrophic agent derived from highly purified porcine brain tissue, consisting of peptides and free amino acids.
Methods
Due to increasing respiratory insufficiency, the patient was transferred from the stroke unit to the intensive care unit (ICU) on day 23, five days after the stroke.
Scale or participants
Not reported in the reviewed source.
Key findings
Insect stings and drugs are the primary anaphylaxis-causing substances in adults [1].
Limitations and uncertainty
Noradrenaline was chosen as a vasopressor by the ICU physician because the patient had pronounced tachycardia and it was not clear initially whether it was caused by atrial fibrillation or sinus arrhythmia.
Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.