Study type: In vivo/preclinical · Status: Verified against declared source
Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
Restorative neurology and neuroscience · 2017
Study scale: Published data on the age-related changes of neurotrophins and their receptors in rat brain reveal a surprising discrepancy between the results of different research groups.
Abstract only: Open source record
Product or molecular entity relationships
- Cerebrolysin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Plain-language verified summary
Question
The aim of the present study was to examine the age-related modifications of endogenous neurotrophin systems in the brain of male Wistar rats and the effects of CBL on learning and memory as well as the levels neurotrophins and their receptors.
Methods
Published data on the age-related changes of neurotrophins and their receptors in rat brain reveal a surprising discrepancy between the results of different research groups.
Scale or participants
Published data on the age-related changes of neurotrophins and their receptors in rat brain reveal a surprising discrepancy between the results of different research groups.
Key findings
Aging is associated with some cognitive decline and enhanced risk of development of neurodegenerative diseases.
Limitations and uncertainty
Aging is associated with some cognitive decline and enhanced risk of development of neurodegenerative diseases.
Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.