Study type: In vitro · Status: Verified against declared source

Cathelicidin Contributes to the Restriction ofin Human Host Macrophages.

Frontiers in immunology · 2019

Study scale: The human cathelicidin is expressed by monocytes, macrophages as well as neutrophils (17, 33).

Product or molecular entity relationships

LL-37: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

The disease Leishmaniasis is still affecting 12 million people worldwide, of which up to 30,000 cases die yearly (1, 2).

Methods

The disease Leishmaniasis is still affecting 12 million people worldwide, of which up to 30,000 cases die yearly (1, 2).

Scale or participants

The human cathelicidin is expressed by monocytes, macrophages as well as neutrophils (17, 33).

Key findings

In cutaneous Leishmaniasis the parasitic control in human host macrophages is still poorly understood.

Limitations and uncertainty

The disease Leishmaniasis is still affecting 12 million people worldwide, of which up to 30,000 cases die yearly (1, 2).

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.