Study type: Human research · Status: Verified against declared source

Dose-dependent social-cognitive effects of intranasal oxytocin delivered with novel Breath Powered device in adults with autism spectrum disorder: a randomized placebo-controlled double-blind crossover trial

2017

Study scale: Another barrier to the translation of pre-clinical oxytocin research relates to the study design issues.

Product or molecular entity relationships

Oxytocin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

We had two primary outcome measures: an overt emotion sensitivity task previously demonstrated to be modulated by oxytocin delivered via the Breath Powered device40 and a Norwegian translation of the RMET49 a commonly used task in oxytocin research17, 19, 26, 50, 51 to assess theory of mind performance.

Methods

The neuropeptide oxytocin has shown promise as a treatment for symptoms of autism spectrum disorders (ASD).

Scale or participants

Another barrier to the translation of pre-clinical oxytocin research relates to the study design issues.

Key findings

The neuropeptide oxytocin has shown promise as a treatment for symptoms of autism spectrum disorders (ASD).

Limitations and uncertainty

The neuropeptide oxytocin has shown promise as a treatment for symptoms of autism spectrum disorders (ASD).

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.