Study type: Human research · Status: Verified against declared source

Impaired Glutathione Synthesis in Neurodegeneration

2013

Study scale: Not reported

Abstract only: Open source record

Product or molecular entity relationships

Glutathione: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Not reported in the reviewed source.

Methods

Clinically, inborn errors in the GSH-related enzymes are very rare whereas disorders in GSH metabolism are common in some neurodegenerative diseases showing GSH depletion and increased levels of oxidative stress in the CNS (Figure 2).

Scale or participants

Not reported in the reviewed source.

Key findings

Glutathione (GSH) was discovered in yeast cells in 1888.

Limitations and uncertainty

Glutathione (GSH) was discovered in yeast by two independent scientists over a century ago.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.