Study type: In vitro · Status: Verified against declared source

LL-37 regulates odontogenic differentiation of dental pulp stem cells in an inflammatory microenvironment.

Stem cell research & therapy · 2024

Study scale: The ability of LL-37 to promote the migration of DPSCs was evaluated via a transwell assay and microscopic observation at 24 and 48 h.

Abstract only: Open source record

Product or molecular entity relationships

LL-37: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Inflammation often causes irreversible damage to dental pulp tissue.

Methods

DPSCs were isolated via enzyme digestion combined with the tissue block adhesion method and identified via flow cytometry.

Scale or participants

The ability of LL-37 to promote the migration of DPSCs was evaluated via a transwell assay and microscopic observation at 24 and 48 h.

Key findings

Inflammation often causes irreversible damage to dental pulp tissue.

Limitations and uncertainty

Inflammation often causes irreversible damage to dental pulp tissue.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.