Study type: In vivo/preclinical · Status: Verified against declared source

Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing.

Investigative ophthalmology & visual science · 2023

Study scale: Vision correcting refractive surgeries are becoming more popular globally, with annual surgical case numbers reaching over 7 million.

Abstract only: Open source record

Product or molecular entity relationships

VIP: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

R language (version 4.0.3) was used to conduct the bioinformatics analysis.

Methods

Dry eye syndrome (DES) is a prevalent postoperative complication after myopic corneal refractive surgeries and the main cause of postoperative dissatisfaction.

Scale or participants

Vision correcting refractive surgeries are becoming more popular globally, with annual surgical case numbers reaching over 7 million.

Key findings

UCNV significantly induced bilateral decreases in tear secretion.

Limitations and uncertainty

Currently, a growing body of literature reports that corneal nerve severing plays a major role in post refractive surgery dry eye.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.