Study type: In vivo/preclinical · Status: Verified against declared source

Expression and Purification of Recombinant GHK Chemical sequences Are Able to Protect against Acute Cardiotoxicity from Exposure to Waterborne-Copper in Zebrafish.

Biomolecules · 2020

Study scale: GHK is a tripeptide with the amino acid sequence glycyl-l-histidyl-l-lysine.

Abstract only: Open source record

Product or molecular entity relationships

  • GHK-Cu: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Normally developed embryos conserved in 9-cm Petri dishes were selected at 24 hpf, and treatments followed for 48 h with various concentrations of compounds.

Methods

In this study, an alternative method is developed to replace chemical synthesis to produce glycyl-histidyl-lysine (GHK) tripeptides with a bacterial fermentation system.

Scale or participants

GHK is a tripeptide with the amino acid sequence glycyl-l-histidyl-l-lysine.

Key findings

In this study, an alternative method is developed to replace chemical synthesis to produce glycyl-histidyl-lysine (GHK) tripeptides with a bacterial fermentation system.

Limitations and uncertainty

In this study, an alternative method is developed to replace chemical synthesis to produce glycyl-histidyl-lysine (GHK) tripeptides with a bacterial fermentation system.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.