Study type: Human research · Status: Verified against declared source

Humanin and diabetes mellitus: A review ofandstudies.

World journal of diabetes · 2022

Study scale: Core Tip: Humanin (HN) exerts cyto-protective and anti-apoptotic effects.

Abstract only: Open source record

Product or molecular entity relationships

  • Humanin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Humanin (HN) is a 24-amino acid mitochondrial-derived polypeptide with cyto-protective and anti-apoptotic effects that regulates the mitochondrial functions under stress conditions.

Methods

Not reported in the reviewed source.

Scale or participants

Core Tip: Humanin (HN) exerts cyto-protective and anti-apoptotic effects.

Key findings

Humanin (HN) is a 24-amino acid mitochondrial-derived polypeptide with cyto-protective and anti-apoptotic effects that regulates the mitochondrial functions under stress conditions.

Limitations and uncertainty

The first attempt to measure HN levels in a clinical population with impaired fasting glucose (IFG) was made in participants attending a diabetes complications screening clinic (DiabHealth)[67,68].

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.