Study type: Human research · Status: Verified against declared source

A novel link between chronic inflammation and humanin regulation in children.

Frontiers in endocrinology · 2023

Study scale: Humanin levels were decreased in serum of IBD patients.

Abstract only: Open source record

Product or molecular entity relationships

Humanin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Not reported in the reviewed source.

Methods

Total RNA was extracted from harvested HCS-2/8 cells using TRIzol reagent (15596026; Thermo Fisher Scientific, Waltham, Massachusetts, USA) according to the manufacturer’s instruction.

Scale or participants

Humanin levels were decreased in serum of IBD patients.

Key findings

Humanin levels were measured by ELISA in serum from 40 children with IBD and 40 age-matched healthy controls.

Limitations and uncertainty

To our knowledge, there is no previous evidence supporting any link between chronic inflammation and humanin regulation.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.