Study type: Human research · Status: Evidence verified by machine against declared source
Oxytocin and social functioning
Dialogues in clinical neuroscience · 2017
Study scale: Not published. The text held for this field did not answer this heading, so nothing is shown here and nothing is substituted for it.
Abstract only: Open source record
Product or molecular entity relationships
- Oxytocin: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.
Public plain-language summary
Some fields are not published, because the text held for them did not answer their heading. The published text is limited to the declared source and preserves reported uncertainty. It does not establish efficacy, safety, suitability, or evidence strength.
Research question
Not reported in the declared source.
Study design
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Participants or experimental system
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Study scale
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Intervention or exposure
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Comparator
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Outcomes examined
Animal studies have examined the role of oxytocin in a variety of mammals, including sheep, mice, and rats.15 Prairie voles have been of particular interest in oxytocin animal research because they demonstrate selective social preference in order to survive and reproduce in their habitats.16,17 Early animal studies demonstrated oxytocin's ability to induce the prosocial behavior of bonding, both maternal bonding with offspring and pair bonding.18-20 In voles, pair bonding is measured by time spent in proximity of a partner versus a stranger, in which more time spent with a partner indicates pair-bond formation.21,22 Pair bonding can be induced in female voles via intracerebroventricular oxytocin injection, or prevented by an oxytocin receptor antagonist in the nucleus accumbens and prefrontal cortex.20,23 Maternal/infant bonding has also been demonstrated in voles.24 Individuals with social anxiety disorder, as well as other disorders such as autism, can struggle with forming and maintaining interpersonal relationships.
Key findings
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Limitations and uncertainty
Not published. The text held for this field did not answer this heading, so nothing is shown here and nothing is substituted for it.
Product relevance and evidence boundary
This record is a published study, held here with its citation and review status. It is not a statement that any catalog item is effective, safe, or suitable for any use, and nothing in it is a dose or a protocol.
Evidence verified by machine against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.