Study type: In vivo/preclinical · Status: Verified against declared source

Retinoprotective Effects of TAT-Bound Vasoactive Intestinal Chemical sequence and Pituitary Adenylate Cyclase Activating Chemical sequence.

Journal of molecular neuroscience : MN · 2019

Study scale: Fourteen days after the operation, rats (n = 10 SHAM and n = 24 BCCAO) were killed with anesthetic and the eyes were processed for histology.

Abstract only: Open source record

Product or molecular entity relationships

VIP: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

PACAP in the form of eye drops has first been shown to exert local effects on the cornea.

Methods

Not reported in the reviewed source.

Scale or participants

Fourteen days after the operation, rats (n = 10 SHAM and n = 24 BCCAO) were killed with anesthetic and the eyes were processed for histology.

Key findings

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) belong to the same peptide family and exert a variety of biological functions.

Limitations and uncertainty

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) belong to the same peptide family.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.