Study type: Human research · Status: Verified against declared source

Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial.

PloS one · 2015

Study scale: The study was approved by the Research and Ethical Review Committees at the International Centre for Diarrheal Disease Research, Bangladesh (icddr,b).

Abstract only: Open source record

Product or molecular entity relationships

LL-37: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Tuberculosis (TB) is a global pandemic disease caused by Mycobacterium tuberculosis (Mtb) that is responsible for almost 9 million active pulmonary TB cases worldwide and about 1.5 million died from the disease in 2013 [1].

Methods

The study was approved by the Research and Ethical Review Committees at the International Centre for Diarrheal Disease Research, Bangladesh (icddr,b).

Scale or participants

The study was approved by the Research and Ethical Review Committees at the International Centre for Diarrheal Disease Research, Bangladesh (icddr,b).

Key findings

Development of new tuberculosis (TB) drugs and alternative treatment strategies are urgently required to control the global spread of TB.

Limitations and uncertainty

There were no differences in the occurrence and distribution of most of the AEs between the study arms (Table 2).

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.