Study type: In vivo/preclinical · Status: Verified against declared source

Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37.

PloS one · 2011

Study scale: Cathelicidins have been shown to elicit a number of protective mechanisms in host defense against infection.

Abstract only: Open source record

Product or molecular entity relationships

LL-37: Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

In summary, this study demonstrates that cathelicidins possess potent antiviral activity against influenza virus.

Methods

Not reported in the reviewed source.

Scale or participants

Cathelicidins have been shown to elicit a number of protective mechanisms in host defense against infection.

Key findings

The extensive world-wide morbidity and mortality caused by influenza A viruses highlights the need for new insights into the host immune response and novel treatment approaches.

Limitations and uncertainty

Cathelicidins have been shown to elicit a number of protective mechanisms in host defense against infection.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.