Study type: In vivo/preclinical · Status: Verified against declared source

Thymosin β4 promotes zebrafish Mauthner axon regeneration by facilitating actin polymerization through binding to G-actin.

BMC biology · 2024

Study scale: Tβ4 is upregulated after axonal injury in both zebrafish and mice.

Abstract only: Open source record

Product or molecular entity relationships

Thymosin Beta-4 (TB500): Exact entity relationship. Legacy citation custody associates this source with the catalog record; no product-relevance conclusion is implied.

Plain-language verified summary

Question

Mauthner cells are examples of individual cells that control a specific behavior [41, 42].

Methods

The online version contains supplementary material available at 10.1186/s12915-024-02045-2.

Scale or participants

Tβ4 is upregulated after axonal injury in both zebrafish and mice.

Key findings

Thymosin beta 4 (Tβ4) is a monomeric actin-binding protein that plays many roles in biological activities.

Limitations and uncertainty

Thymosin beta 4 (Tβ4) is a monomeric actin-binding protein that plays many roles in biological activities.

Verified against declared source. Verification is limited to the declared source and review scope. It does not mean independent replication or establish efficacy, safety, or suitability.