Research chemical sequence
Melanotan II
Melanotan II is listed as a research-use-only chemical sequence. Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
Research-use boundary: Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
Public identity
- Publication state
- unpublished
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Available variants
| Size | SKU | Price (USD) | Availability | Representative purity |
|---|---|---|---|---|
| 10mg | DFP-039 | $0.00 | Out of stock | 99.2% |
Analytical boundary
Representative catalog purity: 99.2%
No active-batch certificate of analysis is currently published.
Purity figures shown here are representative catalog specifications, not lot-specific measurements.
Evidence inventory
- Record state
- reviewed records
- Public records
- 797
- Reviewed summaries
- 15
- Verified citations
- 0
- Human study: 34
- In vivo: 528
- In vitro: 235
- Special category: 0
- Unclassified: 0
These counts describe linked records and review status. They do not establish efficacy, safety, or fitness for any use.
Technical record
- Molecular weight
- 1024.18 Da
- Sequence class
- peptide
- Appearance
- Lyophilized Solid
- Solubility
- Water, PBS, or 0.9% NaCl
- Mechanism record
- Melanotan II is a synthetic cyclic 7-residue chemical sequence analog of alpha-MSH with non-selective activity at MC1R (tanning), MC3R (metabolic), MC4R (appetite/sexual function), and MC5R (exocrine). The cyclic lactam bridge between Asp and Lys residues enhances metabolic stability vs. linear α-MSH. Binding MC1R activates adenylyl cyclase → cAMP → PKA → CREB → MITF cascade, upregulating eumelanin synthesis in melanocytes.
- Half-life record
- ~2 hours
Recorded receptors
- MC1R tanning
- MC3R metabolic
- MC4R appetite/sexual
- MC5R exocrine
External literature records
- External literature record
- External literature record
Limitations and research boundary
Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
External records are attributed references. Their presence does not convert a source-reported observation into a product claim.