Research chemical sequence
Semax
Semax is listed as a research-use-only chemical sequence. Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
Research-use boundary: Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
Public identity
- Publication state
- unpublished
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
- IUPAC name
- L-Methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-prolyl-glycyl-L-proline
- Molecular formula
- C37H51N9O10S
Available variants
| Size | SKU | Price (USD) | Availability | Representative purity |
|---|---|---|---|---|
| 10mg | DFP-011 | $0.00 | Out of stock | 99.8% |
Analytical boundary
Representative catalog purity: 99.8%
No active-batch certificate of analysis is currently published.
Purity figures shown here are representative catalog specifications, not lot-specific measurements.
Evidence inventory
- Record state
- reviewed records
- Public records
- 521
- Reviewed summaries
- 11
- Verified citations
- 0
- Human study: 46
- In vivo: 367
- In vitro: 108
- Special category: 0
- Unclassified: 0
These counts describe linked records and review status. They do not establish efficacy, safety, or fitness for any use.
Technical record
- CAS number
- 80714-61-0
- Molecular weight
- 813.9 Da
- Sequence class
- peptide
- Molecular formula
- C37H51N9O10S
- Appearance
- White to off-white lyophilized powder.
- Solubility
- Hydrophilic. Readily soluble in sterile distilled water or physiological saline (pH 6.0-8.0) at concentrations up to 10 mg/mL. For optimal stability, reconstitute immediately prior to use and avoid repeated freeze-thaw cycles.
- Mechanism record
- Semax is a synthetic ACTH(4-10)-Pro-Gly-Pro analogue that rapidly upregulates BDNF and NGF in the hippocampus and cortex. It activates MC4R (melanocortin 4 receptor) and TrkB (BDNF receptor), modulating dopamine D1/D2 signaling. The Pro-Gly-Pro C-terminal extension enhances metabolic stability against carboxypeptidases, extending intranasal effective duration to 30-60 minutes.
- Half-life record
- ~1 hour
Recorded receptors
- MC4R
- TrkB (BDNF)
- Dopamine D1/D2
External literature records
- External literature record
- External literature record
Limitations and research boundary
Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.
External records are attributed references. Their presence does not convert a source-reported observation into a product claim.