Thymosin Alpha 1

Public identity

Publication state

unpublished

Sequence

Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn

Available variants

Analytical boundary

Representative catalog purity: 99.7%

No active-batch certificate of analysis is currently published.

Purity figures shown here are representative catalog specifications, not lot-specific measurements.

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Evidence inventory

Record state

reviewed records

Public records

638

Reviewed summaries

18

Verified citations

0

• Human study: 172
• In vivo: 235
• In vitro: 231
• Special category: 0
• Unclassified: 0

These counts describe linked records and review status. They do not establish efficacy, safety, or fitness for any use.

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Technical record

Molecular weight

3108.4 Da

Sequence class

peptide

Appearance

Lyophilized Solid

Solubility

Water, PBS, or 0.9% NaCl

Mechanism record

Thymosin Alpha 1 (Tα1) is a 28-amino-acid chemical sequence originally isolated from thymic tissue (thymosin fraction 5). It activates innate immunity via TLR2/TLR9 signaling on dendritic cells, promotes T-cell maturation and CD4+/CD8+ differentiation, enhances NK cell cytotoxicity, and stimulates antibody production. FDA-approved outside the US as Zadaxin for hepatitis B and used as an immune adjuvant.

Half-life record

~2-3 hours

Recorded receptors

• TLR2/TLR9
• DC maturation
• NK cell activation

External literature records

1. External literature record
2. External literature record

Limitations and research boundary

Research use only. Not for human or veterinary use. Public catalog information is limited to chemical identity, analytical documentation, and external reference records.

External records are attributed references. Their presence does not convert a source-reported observation into a product claim.